THIOFLAVIN T

        Safety Data Sheet   
Emergency Telephone Number: CHEMTREC 1-800-424-9300	For Information call: DUDLEY 732-886-3100       
        DUDLEY CORPORATION        
         	      125 Kenyon Drive	
               Lakewood, New Jersey 08701
Effective Date: January 1, 2025
1. PRODUCT: Syn:  C.I. 49005; Basic Yellow 1; Thioflavine TCN; Primoflavine T; Rhoduline Yellow 6G; Setoflavin T; Tannoflavin T	CAS No.:  2390-54-7   Weight:  318.9   Ec no.: 219-228-9  Formula:  C17H19CIN2S

2.HAZARDS: GHS Class: Acute Toxcity, Oral (Cat 3), Serious eye damage (Cat 1), Skin Sensitization (Cat 1), 
Acute and Chronic aquatic hazard (Cat 1)
Pictogram :   				
Signal Word: Danger 

Hazard statement(s) H301 Toxic if swallowed. H317 May cause an allergic skin reaction. H318 Causes serious eye damage. H410 Very toxic to aquatic life with long lasting effects. 

Precautionary statement(s) P261 Avoid breathing dust. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P272 Contaminated work clothing must not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/ eye protection/ face protection. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. Rinse mouth. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor. P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention. P363 Wash contaminated clothing before reuse. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal

HMIS Class: Health hazard  0, Flammability   0,  Physical hazards   0			
NFPA Rating: Health hazard  0, Fire     0, Reactivity hazard   0

Potential Effects: Eye: Risk of serious damage to eyes.	Skin: Harmful in contact with skin. 
Ingestion: Harmful if swallowed. 		Inhalation: Harmful by inhalation. 
2.3: Other Hazards: none

3. COMPOSITION, INFO ON INGREDIENTS:
Chemical  			CAS No.			Percent			Hazardous
Thioflavine T			2390-54-7		90 – 100%		       No 	

4. FIRST AID: Eyes: rinse immediately with plenty of water Skin: Rinse with plenty of soap & water Ingestion: Do not induce vomiting w/o medical advice. Rinse with water. Inhalation: Move to fresh air.  Consult a physician. Physician: Treat symptomatically & supportively. 

5. FIRE FIGHTING: Info: wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH & full PPE. Water mist may be used to cool closed containers. Extinguishing: Use dry chem, CO2, water spray or alcohol resistant foam.  Haz:  Carbon oxides, Sulphur & nitrogen oxides, hydrogen chloride gas.                    

6. ACCIDENTAL RELEASE: Info: Use proper PPE as indicated in Section 8. Spills: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. 

7. HANDLING & STORAGE: Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation.  Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion & inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatibles. 

8. EXPOSURE: Facilities storing or utilizing this material should be equipped with an eyewash facility and safety shower. Use adequate ventilation to keep airborne concentrations low.
Chemical 				ACGIH		NIOSH		OSHA – Final/Vacated PEL’s
Thioflavine T				None listed	None listed	None listed

PPE: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirators when necessary. 

9. PHYSICAL & CHEM: Appearance: Yellow to gold-yellow to orange-brown powder.

10. STABILITY & REACTIVITY: Stability: Stable at room temp in closed containers under normal storage/handling conditions. Avoid: Incompatibles Incompatibilities: Strong oxidizing agents Haz Decomp: see sec 5

11. TOXIC INFO: RTECS: Unlisted  LD50/LC50: N/A
Carcinogenicity: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. 

12. ECOLOGICAL INFO:  N/A

13. DISPOSAL CONSIDERATIONS: Chem waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed. 

14. TRANSPORT INFO: DOT: UN2811, Toxic solids, organic, n.o.s. (Thioflavin T), 6.1, III
IMDG: UN2811, Toxic solids, organic, n.o.s. (Thioflavin T), 6.1, III

IATA: UN2811, Toxic solids, organic, n.o.s. (Thioflavin T), 6.1, III

15. REGULATORY INFO: SARA 311/312: None
SARA Section 302 Extremely Haz None of the chemicals in this product have a TPQ/RQ.
Section 313 No chemicals are reportable under Section 313. STATE is not present on state lists from CA, MN, MA, FL. 
PA / NJ  Right to Know:	Thioflavin T  CAS#2390-54-7 		
California Prop.65: None of the chemicals are known to cause cancer, birth defects, or any other reproductive harm. 

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives 
Hazardous Symbols:  Not available.WGK (Water Danger/Protection) CAS#2390-54-7:  No information available.  
Canada - DSL/NDSL CAS#2390-54-7 is listed on Canada’s DSL List. 
Canada - WHMIS:  Not available. CAS#2390-54-7  is not listed on Canada’s Ingredient Disclosure List. 

16. DISCLAIMER INFO: DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information.