THIAZOLYL BLUE TETRAZOLIUM BROMIDE

Safety Data Sheet
Emergency Telephone Number: CHEMTREC 1-800-424-9300       For Information call: DUDLEY 732-886-3100       
      DUDLEY CORPORATION
           	       125 Kenyon Drive
       				         	       Lakewood, New Jersey 08701
Effective Date: January 1, 2025	
1. PRODUCT: Syn:  MTT , 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide, Methylthiazolyldiphenyl-tetrazolium bromide CAS No.: 298-93-1  E-C No.:206-069-5 Weight:  414.32g/mol Formula: C18H16BrN5SC18H16BrN5S

2. HAZARDS: GHS:  Skin irritation (Category 2) Eye irritation (Category 2A) Germ Cell mutagenicity (Category 2)			       Specific target organ toxicity - single exposure (Category 3)
 Pictogram: 			                		
Signal Word:         WARNING
HAZARD STATEMENT: H319: Causes serious eye irritation.  H315: Causes skin irritation
H335: May cause respiratory irritation	H341: Suspected of causing genetic effects.
PRECAUTIONARY STATEMENT: P201: Obtain special instructions before use. P264: Wash skin thoroughly after handling.
P202: Do not handle until all safety precautions have been read and understood. P405: Store locked up. P261: Avoid breathing dust/spray/ fume/gas/ mist/ vapors. P271: Use only outdoors or in well-ventilated area. P280: Wear protective gloves/eye & face protection. P302 + P352: If on skin gently wash with plenty of soap & water. P304 + P340: If inhaled: remove to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: If in Eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present & easy to do so. Continue rinsing. P308 +P313: If exposed or concerned: contact doctor/physician. P321: Specific treatment (see supplemental first aid instructions). P332 + P313: If skin irritation occurs: consult physician.   P337 + P313: If eye irritation occurs: consult physician P362: Take off contaminated clothing and wash before reuse. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P501: Dispose of contents/container to an approved waste disposal plant.

HMIS Class: Health hazard  2, Flammability   0,  Physical hazards   0			
NFPA Rating: Health hazard  2, Fire     0, Reactivity hazard   0

Potential Effects: Eye: Risk of serious damage to eyes.  Skin: Harmful in contact with skin. Ingestion: Harmful if swallowed. 		               Inhalation: Harmful by inhalation. 
2.3: Other Hazards: none

3. COMPOSITION/INFO
Chemical 							CAS No.		Percent
3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide 		298-93-1	   	98%                

4. FIRST AID: Eyes: Rinse immediately with plenty of water and seek medical advice. Skin: Rinse with plenty of soap & water and seek medical advice. Ingestion: Do not induce vomiting without medical advice. Rinse with water. Consult physician. Inhalation: Move to fresh air.  Physician: Treat symptomatically and supportively. 

5. FIRE FIGHTING:  Info: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH & full PPE. Irritating & toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.  Haz: Carbon, nitrogen & sulfur oxides, hydrogen bromide gas. Extinguishing: Use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam. 

6. ACCIDENTAL RELEASE: Info: Use proper PPE as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the PPE Section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.  

7. HANDLING & STORAGE: Handling: Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion & inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatibles.  Light sensitive. Air and moisture sensitive.

8. EXPOSURE: Use adequate ventilation to keep airborne concentrations low. 
Chemical							 ACGIH     NIOSH   OSHA-Final/ Vacated PELs 
3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide	 None       None                 None 

PPE:  Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure.  0.11mm thick nitrile. Clothing: Wear appropriate protective clothing to prevent skin exposure. 
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirators when necessary. 

9. PHYSICAL & CHEM: Appearance: Yellow powder. Melting Pt: 195˚C(383˚F) 

10. STABILITY & REACTIVITY: Stability: Stable under normal temp/pressures. Avoid: Incompatibles, dust generation, excess heat, strong oxidants. Incompatibilities: Oxidizing agents. Haz Decomp: see section 5

11. TOXICOLOGICAL INFO: RTECS#: XF8060000. LD/LC50: No data Mutagenicity: S. typhimurium positive
Carcinogenicity: CAS# 298-93-1: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. 

12. ECOLOGICAL INFO: N/A

13. DISPOSAL CONSIDERATIONS: Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. 
RCRA P-Series: None listed. RCRA U-Series: None listed. 

14. TRANSPORT REGULATIONS: Not dangerous goods

15. REGULATORY INFO: SARA 311/312: Acute & chronic health hazard Section 302 None of the chemicals in this product have a TPQ. Section 313 No chemicals are reportable under Section 313. 
STATE CAS# 298-93-1 is not present on state lists from CA, MN, MA, FL. 
Pa/NJ Right to Know:  3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide CAS#298-93-1
California Prop.65: None of the chemicals are known to cause cancer, birth defects, or any other reproductive harm.

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives 
Hazard Symbols: N/A	WGK (Water Danger/Protection) CAS# 298-93-1: 2 
Canada - DSL/NDSL CAS# 298-93-1 is listed on Canada’s NDSL List. Canada - WHMIS: Not available. 
Canadian Ingredient Disclosure List: No data available. 

16. DISCLAIMER INFO: DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information.