NINHYDRIN

Safety Data Sheet
Emergency Telephone Number: CHEMTREC 1-800-424-9300       For Information call: DUDLEY 732-886-3100       
      DUDLEY CORPORATION
           	       125 Kenyon Drive
       				         	       Lakewood, New Jersey 08701
Effective Date: January 1, 2025	
1. PRODUCT ID: Syn:  2,2-Dihydroxy-1,3-indanedione, 1,2,3-Indantrione, Trioxohydrindene 	CAS No.: 485-47-2 
E-C No.: 207-618-1	Weight:  178.14g/mol 	Formula: C9H6O4

2. HAZARDS ID: GHS Class: Acute toxicity, Oral (Category 4) Skin irritation (Category 2) Eye irritation (Category 2A)	
 Pictogram: 				                      
Signal Word:         WARNING
HAZARD STATEMENT: H302: Harmful if swallowed.  H319: Causes serious eye irritation.  H315: Causes skin irritation	
PRECAUTIONARY STATEMENT: P264: Wash skin thoroughly after handling. P270: Do not drink, eat, smoke, when using this product.  P280: Wear protective gloves/eye & face protection.  P330: Rinse mouth.  P301 + P312: If swallowed: Call Poison Center or doctor/physician if you feel unwell.  P302 + P352: If on skin gently wash with plenty of soap & water. P332 + P313: If skin irritation occurs: consult physician.   P337 + P313: If eye irritation occurs: consult physician.
P362: Take off contaminated clothing & wash before reuse. P501: Dispose of contents/container to an approved waste disposal plant.

HMIS: Health hazard  2, Flammability   0,  Physical hazards   0			
NFPA Rating: Health hazard  2, Fire     0, Reactivity hazard   0
2.3: Other Hazards: none

3. COMPOSITION / INFO: 
Chemical 				 CAS No.	 	Percent		
Indan-1,2,3-trione		                  485-47-2                   90-100%                  

4. FIRST AID: Eyes: Rinse for 15 min. with plenty of water. Skin: Rinse with plenty of soap & water. Ingestion: Do not induce vomiting w/o medical advice. Rinse with water. Consult physician. Inhalation: Move to fresh air.  Physician: Treat symptomatically & supportively. 

5. FIRE FIGHTING: Info: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH & full PPE.  Irritating & highly toxic gases may be generated by thermal decomp/combustion. Hazards: Carbon oxides. Extinguishing: Use water spray, dry chem Carbon dioxide, or alcohol-resistant foam. Flash Pt: N/A Auto-ignition Temp:  N/A. Explosion Limits:  N/A.

6. ACCIDENTAL RELEASE: Info:  Use proper PPE as indicated in Section 8. Spill:  Vacuum or sweep up material and place into a suitable disposal container.  Clean up spills immediately, observing precautions in the PPE section.  Avoid generating dusty conditions.  Provide ventilation.

7. HANDLING & STORAGE: Handling:  Wash thoroughly after handling.  Use with adequate ventilation.  Minimize dust generation and accumulation.  Avoid contact with eyes, skin, and clothing.  Keep container tightly closed.  Avoid ingestion and inhalation. Storage:  Store in a tightly closed container.  Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.  Light sensitive.
  
8. EXPOSURE: Facilities storing or utilizing this material should be equipped with any eyewash facility and safety shower.  Use adequate ventilation to keep airborne concentrations low.
 Chemical 		ACGIH			NIOSH		OSHA – FINAL /Vacated PEL’s
 Ninhydrin		None listed		None listed	   None listed

 PPE: Eyes:  Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection      regulations in 29 CFR 1910.133 or European Standard EN 166. Skin:  Wear appropriate protective gloves to prevent skin exposure. 0.11mm thick nitrile. Clothing:  Wear appropriate protective clothing (lab coats, coveralls) to prevent skin exposure. Respirators:  Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149.  Always use a NIOSH or European Standard EN 149 Approved respirator, when necessary. 

  9. PHYSICAL & CHEM: White to yellowish-white crystals.  Odor: Characteristic odor.   Melting Pt:  250˚C (466° F) 

10. STABILITY & REACTIVITY: Stability: Stable at room temp under normal storage & handling. May discolor on exposure to light.  Avoid:  Excess heat, dust generations, incompatibles, light. Incompatibilities:  Strong oxidizing agents, bases, amines. 
 Haz Decomp: see section 5

11. TOXICOLOGICAL INFO: RTECS: NK5425000	LD50/LC50: LD50- Oral-Rat-600 mg/kg
Carcinogenicity: Not list by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology:  Skin corrosion/irritation & Moderate eye irritation Other:  May cause respiratory irritation

12. ECOLOGICAL INFO: No information available. 

13. DISPOSAL CONSIDERATIONS: Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste.  US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.  Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. 
RCRA P-Series:  None listed. RCRA U-Series:  None listed.

14. TRANSPORT REGULATIONS: Not regulated.  

15. REGULATORY INFO: SARA 311/312: Acute Health Hazard
SARA Section 302 Extremely Hazardous Substances None of the chemicals in this product have a TPQ/RQ.
Section 313 No chemicals are reportable under Section 313.
STATE is not present on state lists from CA, MN, MA, FL. 
PA & NJ Right to Know:  Indan-1,2,3-trione  CAS#485-47-2
California Prop.65: None of the chemicals are known to cause cancer, birth defects, or any other reproductive harm.

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives
Hazardous Symbols  XN	WGK (Water Danger/Protection) CAS#485-47-2:   2
Canada – DSL/NDSL: CAS#485-47-2 is listed on Canada DSL List.
Canada – WHMIS: This product has a WHMIS classification of D1B, D2B.  - is not listed Canada’s Ingredient Disclosure List.

16. DISCLAIMER INFO: DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information.