FLUOREXON/CALCEIN                         
 Safety Data Sheet   
Emergency Telephone Number: CHEMTREC 1-800-424-9300                   For Information call: DUDLEY 732-886-3100       

     DUDLEY CORPORATION        
         	       125 Kenyon Drive
       				          	       Lakewood, New Jersey 08701

Effective Date: January 1, 2025
1. PRODUCT ID: Syn: Bis[N,N-bis(carboxymethyl)aminomethyl]fluorescein; Calcein; Fluorescein complexone; Fluorescein-methylene-iminodiacetic acid. CAS No.:1461-15-0 Weight:  622.55 Formula: C30H26N2O13

2. HAZARDS ID: GHS:  Not a hazardous substance or mixture.
	
HMIS Classification: Health hazard  0, Flammability   0,  Physical hazards   0			
NFPA Rating: Health hazard  0, Fire     0, Reactivity hazard   0
2.3: Other Hazards: none

3. COMPOSITION, INFO:
Chemical Name 			CAS No.		Percent		Hazardous
Fluorexon			1461-15-0	85-90 %		     No

4. FIRST AID: Eyes: Rinse with plenty of water as precaution. Skin: Rinse with plenty of soap & water. 
Ingestion: Do not induce vomiting without medical advice. Rinse with water. Inhalation: Move to fresh air.  
Physician: Treat symptomatically & supportively. 

5. FIRE FIGHTING: Info: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH & full PPE. Irritating & highly toxic gases may be generated by thermal decomposition or combustion.  Runoff from fire control or dilution water may cause pollution. Hazards: Carbon & Nitrogen oxides. Extinguishing: Use water spray, dry chemical, alcohol-resistant foam, or carbon dioxide Flash Pt: N/A. Auto-ignition Temp: N/A Explosion Limits: N/A

6. ACCIDENTAL RELEASE: Info: Use proper PPE as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. 

7. HANDLING & STORAGE: Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Storage: Keep away from heat. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatibles. 

8. EXPOSURE, PPE: Facilities storing or utilizing this material should be equipped with an eyewash facility and safety shower. Use adequate ventilation to keep airborne concentrations low.

Chemical Name				ACGIH		NIOSH		OSHA – Final/Vacated PEL’s
Fluorexon				None listed	None listed	None listed

PPE: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.  Skin: Wear appropriate protective gloves to prevent skin exposure. 0.11mm thick nitrile. Clothing: Wear Appropriate protective clothing to prevent skin exposure. 
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. 

9. PHYSICAL & CHEM: Appearance: Yellow-orange to orange powder Odor: Odorless 

10. STABILITY & REACTIVITY: Haz Decomp: see section 5Stability: Stable at room temp in closed containers under normal storage & handling conditions. Avoid: Incompatibles. Incompatibilities: Strong oxidizing agents. 

11. TOXICOLOGICAL INFO: RTECS: N/A LD50/LC50: N/A Carcinogenicity: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.

12. ECOLOGICAL INFO:  No data available.

13. DISPOSAL CONSIDERATIONS: Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. 
RCRA P-Series: None listed. RCRA U-Series: None listed. 

14. TRANSPORT INFO: Not regulated.

15. REGULATORY INFO: SARA 311/312: None
Section 302None of the chemicals in this product have a TPQ/RQ. 
Section 313 No chemicals are reportable under Section 313. 
STATE CAS# 1461-15-0 is not present on state lists from CA, MN, MA, FL. 
PA & NJ Right to Know:  Fluorescein-bis(methyliminodiacetic acid  CAS# 1461-15-0
California Prop.65 components: None of the chemicals are known to cause cancer, birth defects, or any other reproductive harm.

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives 
Hazardous Symbols: Not available.WGK (Water Danger/Protection) No information available. 
Canada - DSL/NDSLCAS# 1461-15-0 is listed on Canada’s DSL List. 
Canada – WHMIS: Is not available CAS# 1461-15-0 is not listed on Canada’s Ingredient Disclosure List. 

16. DISCLAIMER INFO: DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information