ETHIDIUM BROMIDE

Safety Data Sheet
Emergency Telephone Number: CHEMTREC 1-800-424-9300       For Information call: DUDLEY 732-886-3100       
       DUDLEY CORPORATION
           	        125 Kenyon Drive
       				         	        Lakewood, New Jersey 08701
Effective Date: January 1, 2025	
1. PRODUCT ID: Syn:  Homidium bromide, EtBr, 3,8-Diamino-1-ethyl-6-phenylphenantridinium bromide
CAS No.: 1239-45-8 E-C No.:214-984-6 Weight:  394.31g/mol Formula: C21H20BrN3

2. HAZARDS ID: GHS Class: Acute toxicity, Inhalation (Cat 1) Acute toxicity, Oral (Cat 4)	  Germ cell mutagenicity (Category 2)
 Pictogram: 					
Signal Word:         DANGER
HAZARD STATEMENT(S): H302: Harmful if swallowed. 	H341: Suspected of causing genetic defects. 
H330: May be fatal if inhaled.
PRECAUTIONARY STATEMENT(S):  P202: Do not handle until all safety precautions have been read and understood.
P260: Do not breath dust/spray/ fume/gas/ mist/ vapors. P201: obtain special instructions before use.
P264: wash skin thoroughly after handling.  P270: Do not drink, eat, smoke, when using this product.
P271: Use only outdoors or in well-ventilated area. P405: Store locked up. P280: Wear PPE as required.  
P284: Wear respiratory protection.       P301 + P312: If Swallowed: Call Poison Center or doctor/physician if you feel unwell.
P304 + P340: If inhaled: remove to fresh air and keep at rest in a position comfortable for breathing.	
P310: Immediately Call Poison Center or doctor/physician if you feel unwell.  P308: If exposed, get medical attention. 
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P501: Dispose of contents/container to an approved waste disposal plant.
2.3: Other Hazards: none

3. COMPOSITION / INFO ON INGREDIENTS: 
Chemical Name			 			CAS No.	 	Percent		
3,8-Diamino-1-ethyl-6-phenylphenantridinium bromide	                 1239-45-8                  90-100%                  

4. FIRST AID: Eyes: Rinse immediately with plenty of water and seek medical advice. Skin: Rinse with plenty of soap & water and seek medical advice. Ingestion: Do not induce vomiting without medical advice. Rinse with water. Consult physician. Inhalation: Move to fresh air.  Physician: Treat symptomatically & supportively. 

5. FIRE FIGHTING: Info: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH & full PPE. Irritating & highly toxic gases may be generated by thermal decomp/combustion.  Runoff may cause pollution. Extinguishing: Use water spray to cool fire expose containers.  Use water spray, dry chemical, Carbon dioxide, or alcohol-resistant foam. Flash Pt: N/A Auto-ignition Temp:  N/A Explosion Limits:  Not available. Hazards: Carbon & Nitrogen oxides, Hydrogen bromide gas. 

6. ACCIDENTAL RELEASE: Info: Use proper PPE as indicated in Section 8.  Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Do not let product enter drains. 

7. HANDLING & STORAGE: Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

8. EXPOSURE CONTROLS, PPE: Controls: Facilities utilizing this material should be equipped with an eyewash facility and safety shower. Use adequate ventilation to keep airborne concentrations low.
Chemical Name		ACGIH                	NIOSH                             	OSHA - Final / Vacated PEL’s
Ethidium bromide 		None listed	None listed		None listed

PPE: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Full-face particle respirator.  Skin: Wear appropriate protective gloves to prevent skin exposure. 0.11 mm thick nitrile. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. Hygiene: Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. 

9. PHYSICAL & CHEM: Appearance:  Red to purple powder  pH: 4-7 at 25˚C(77˚F)
Melting Pt:  260 - 262° C (500-504˚F) Solubility:  (in water):  Soluble. 

10. STABILITY & REACTIVITY: Stability: Stable at room temp. in closed containers under normal storage and handling conditions.  Avoid: Incompatibles, heat. Incompatibilities:  Strong oxidizing agents. Hazardous Decomp:  see sec 5

11. TOXICOLOGICAL INFO: RTECS: SF7950000 LD50:  Oral, mouse: 1000 mg/kg Oral, rat:  LD50 = 1,503 – 2,177 mg/kg   Carcinogenicity: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.  Mutagenicity:  Ames-test: positive		

12. ECOLOGICAL INFO: Environmental Fate: No information available.

13. DISPOSAL CONSIDERATIONS: Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. Contact a licensed professional waste disposal service to dispose of this material. 
RCRA P-Series: None listed. RCRA U-Series: None listed. 

14. TRANSPORT: 
DOT:  UN 2811, Toxic solids, organic, n.o.s. (Ethidium bromide), 6.1, I, ERG 154 
IMDG: UN 2811, TOXIC SOLID, ORGANIC, N.O.S. (Ethidium bromide), 6.1, I,    EMS-No. F-A, S-A. 
 IATA:  UN 2811, Toxic solid, organic, n.o.s. (Ethidium bromide), 6.1, I,

15. REGULATORY INFO: SARA 311/312: Acute Health Hazard, Chronic Health Hazard
SARA Section 302 Extremely Hazardous Substances None of the chemicals in this product have a TPQ/RQ.
Section 313 No chemicals are reportable under Section 313. 
STATE CAS# 1239-45-8 is not present on state lists from CA, MN, MA, FL. 
Pa Right to Know:	3,8-Diamino-1-ethyl-6-phenylphenantridinium bromide  CAS#1239-45-8
NJ Right to Know:	3,8-Diamino-1-ethyl-6-phenylphenantridinium bromide  CAS#1239-45-8
California Prop.65 components: None of the chemicals are known to cause cancer, birth defects, or any other reproductive harm.

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives 
Hazardous Symbols:   T+ Very toxic	WGK (Water Danger/Protection) CAS# 1239-45-8:  2 
Canada - DSL/NDSLCAS# 1239-45-8  is not listed on Canada’s DSL List. Canada - WHMIS:  Not available.
CAS# 1239-45-8 is not listed on Canada’s Ingredient Disclosure List. 

16. DISCLAIMER INFO:  DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information.