ERYTHROSIN B

Safety Data Sheet
Emergency Telephone Number: CHEMTREC 1-800-424-9300       For Information call: DUDLEY 732-886-3100       
      DUDLEY CORPORATION
           	     125 Kenyon Drive
       				         	     Lakewood, New Jersey 08701
Effective Date: January 1, 2025
1. PRODUCT: Syn:  Erythrosin extra bluish, Iodoeosin, Acid Red 51, 2’,4’,5’,7’-Tetraiodofluoresceindisodium salt   
CAS No.: 16423-68-0 E-C No.:240-474-8  Weight: 879.86g/mol Formula: C20H6I4.Na2O5

2. HAZARDS: GHS: Chronic aquatic toxicity (Category 2) 	Acute toxicity, Oral (Category 4)	
Acute aquatic toxicity (Category 2)
Pictogram: 				                     
Signal Word:         WARNING
HAZARD STATEMENT(S): H302: Harmful if swallowed. H411: Toxic to aquatic life with long lasting effects. 
PRECAUTIONARY STATEMENT(S): P264: Wash skin thoroughly after handling.  P330: Rinse mouth.
P270: Do not drink, eat, smoke, when using this product. 	P273: Avoid release into the environment.
P301 + P312: If swallowed: Call Poison Center or doctor/physician if you feel unwell. P391: Collect spillage. 
P501: Dispose of contents/container to an approved waste disposal plant.

HMIS Classification: Health hazard  1, Flammability   1,  Physical hazards   0			
NFPA Rating: Health hazard  1, Fire     1, Reactivity hazard   0

Potential Health Effects: Eye: Risk of serious damage to eyes.	Skin: Harmful in contact with skin. 
Ingestion: May be harmful if swallowed. 		Inhalation: May be harmful by inhalation. 
2.3: Other Hazards: none

3. COMPOSITION / INFO: 
Chemical Name							CAS No.	              Percent		
Disodium 2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl)benzoate	                16423-68-0           90-100%          

4. FIRST AID: Eyes: Rinse with plenty of water as precaution. Skin: Rinse with plenty of soap & water Ingestion: 
Do not induce vomiting without medical advice. Rinse with water. Inhalation: Move to fresh air.  Physician: Treat symptomatically & supportively. 

5. FIRE FIGHTING: Info: Wear a self-contained breathing apparatus Extinguishing: use water, dry chemical, chemical foam, or alcohol-resistant foam.  Flash Pt: 182°C closed cup Hazards: Carbon & Sodium oxides, Hydrogen iodide

6. ACCIDENTAL RELEASE: Info: Use proper PPE as indicated in Section 8.  Spills/Leaks: Clean up spills immediately, observing precautions in the PPE Section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.  

7. HANDLING & STORAGE: Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Do not ingest or inhale. Keep from contact with moist air and steam. Do not breathe dust. 
Storage: Keep container closed when not in use. Store protected from moisture. Store in a cool, dry area away from incompatible substances. 

8. EXPOSURE / PPE: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use  adequate ventilation to keep airborne concentrations low. 
Chemical Name                   ACGIH                     NIOSH                   OSHA - Final / Vacated PELs 
Erythrosin B                          None listed            None listed                None listed. 

PPE: Eyes:  Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and fact protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin:  Wear appropriate protective gloves to prevent skin exposure. Nitrile rubber 0.11 mm thick Clothing:  Wear appropriate protective clothing (Labcoat and overalls) to prevent skin exposure.  Respirators:  Follow the OSHA respirator regulations in 29 CFR 1910.134 or European Standard EN 149.  P95 (US) particle respirator Use NIOSH or European Standard EN 149 approved respirator when necessary.

9. PHYSICAL & CHEM: Appearance: Dark red to maroon to brown powder.  pH: 6.4 at 30.3°C Melting Pt: 315°C at 978.5hPa Solubility: Soluble in water. Relative Density: 0.625-0.731g/cm3 at 30.1°C 
Partition coefficient: n-octanol/water:  log Pow: 4,901

10. STABILITY & REACTIVITY: Stability: Stable under normal temp/pressures. Avoid: Incompatibles, strong oxidants, exposure to moist air or water. Incompatibles: Moisture, strong oxidizing agents.  Haz Decomp: See section 5

11. TOXICOLOGICAL INFO: RTECS#: LM5950000 LD50/LC50: Oral, rat – 1,840 mg/kg - convulsions/effect on seizure threshold. Carcinogenicity: CAS# 16423-68-0: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. 
Other Studies: Hypofunction of thyroid, Stomach – Irregularities – based on human evidence. 

12. ECOLOGICAL: Toxicity:  Fish	LC50 – Oryzias latipes – 500 mg/l – 48 h

13. DISPOSAL CONSIDERATIONS: Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed. 

14. TRANSPORT REGULATIONS: Not dangerous goods. 

15. REGULATORY INFO: Section 311/312: Acute Health Hazard, Chronic Hazard
SARA Section 302 (RQ) & 302 (TPQ) None of the chemicals in this material or products have a RQ or TPQ. 
Section 313 No chemicals are reportable under Section 313. 
STATE CAS# 16423-68-0  is not present on state lists from CA, PA, MN, MA, FL, or NJ. 
California No Significant Risk Level: None of the chemicals in this product are listed. 
PA Right To Know: Disodium 2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl)benzoate    CAS#16423-68-0
NJ Right To Know: Disodium 2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl)benzoate     CAS#16423-68-0

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives 
Hazard Symbols: XN  Harmful  WGK (Water Danger/Protection) 
CAS# 16423-68-0 Water Hazard class 1 (Self-assessment): slightly hazardous for water.
Canada - DSL/NDSL: Not available
Canada - WHMIS: Not available. CAS# 16423-68-0 is not listed on Canada’s Ingredient Disclosure List.

16. DISCLAIMER INFO: DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information.