5,5’-DITHIOBIS(2-NITROBENZOIC ACID)

Safety Data Sheet
       Emergency Telephone Number: CHEMTREC 1-800-424-9300       For Information call: DUDLEY 732-886-3100       
      DUDLEY CORPORATION
           	   125 Kenyon Drive
       				         	   Lakewood, New Jersey 08701
Effective Date: January 1, 2025
1. PRODUCT: Syn:  DTNB. 6.6’-Dinitro-3,3’-dithiobenzoic acid, Ellman’s Reagent, Bis(3-Carboxy-4-nitrophenol) disulfide, 3-Carboxy-4-nitrophenyl disulfide. 	CAS No.: 69-78-3   E-C No.:200-714-4 Weight:  396.35g/mol Formula: C14H8N2O8S2

2. HAZARDS ID:  GHS: Not a hazardous substance or mixture.

HMIS Classification: Health hazard  0, Flammability   0,  Physical hazards   0			
NFPA Rating: Health hazard  0, Fire     0, Reactivity hazard   0
2.3: Other Hazards: none

3. COMPOSITION / INFO: 
Chemical Name			 	CAS No.	 	Percent		
3,3’-Dithiobis[6-nitrobenzoic] acid               	69-78-3                       99%                  

4. FIRST AID: Eyes: Rinse with plenty of water as precaution. Skin: Rinse with plenty of soap & water 
Ingestion: Do not induce vomiting without medical advice. Rinse with water. Inhalation: Move to fresh air.  Consult a physician.  Physician: Treat symptomatically & supportively. 

5. FIRE FIGHTING: Info: Wear self-contaminated breathing apparatus Special Hazards:  Carbon, Nitrogen & sulfur oxides. Extinguishing: use water, dry chemical, chemical foam, or alcohol-resistant foam. 

6. ACCIDENTAL RELEASE: Info: Use proper PPE as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Reduce airborne dust and prevent scattering by moistening with water. Clean up spills immediately, observing precautions in the PPE Section. Avoid generating dusty conditions. Provide ventilation.   

7. HANDLING & STORAGE: Handling: Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing & wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.  Storage: Store in a cool, dry place. Keep container closed when not in use. Keep containers tightly closed.  

8. EXPOSURE / PPE:  Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.  

Chemical Name                  			ACGIH                          NIOSH                 OSHA-Final / Vacated PELs 
5,5'-Dithiobis(2- nitrobenzoic Acid)                    None listed                   None listed         None listed

PPE: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. 0.11mm thick nitrile Clothing: Wear appropriate protective clothing to prevent skin exposure. 
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH Or European Standard EN 149 approved respirator when necessary. 

9. PHYSICAL & CHEM: Appearance: Light yellow-Yellow solid.  Melting Pt: 233-243˚C (451-469˚F)  

10. STABILITY & REACTIVITY: Stability: Stable under normal temp/pressures.  Avoid: Incompatibles, excess heat, strong oxidants.  Incompatibilities: Strong oxidizing agents & strong bases. Haz Decomp: See section 5

11. TOXIC INFO: RTECS#: DG9650000. LD50/LC50: LD50-intraperitoneal-mouse-2,080mg/kg 
Carcinogenicity: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. 

12. ECOLOGICAL INFO: No information available.  

13. DISPOSAL CONSIDERATIONS: Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. 
RCRA P-Series: None listed. RCRA U-Series: None listed. 

14. TRANSPORT REGULATIONS:  Not regulated

15. REGULATORY INFO: SARA 311/312: None
Section 302 (RQ) None of the chemicals in this material have an RQ. 
Section 313 No chemicals are reportable under Section 313. 
STATE: CAS# 69-78-3 is not present on state lists from CA, MN, MA, FL. 
PA & NJ Right to Know:  3,3’-Dithiobis[6-nitrobenzoic]acid  CAS#69-78-3
California Prop.65 components: None of the chemicals are known to cause cancer, birth defects, or any 
other reproductive harm.

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives 
WGK (Water Danger/Protection) CAS# 69-78-3: 1. 
Canada - DSL/NDSL CAS# 69-78-3 is listed on Canada’s DSL List. 
Canada - WHMIS: Not available. 

16. DISCLAIMER INFO: DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information.