ANTIPYRINE 
Safety Data Sheet
Emergency Telephone Number: CHEMTREC 1-800-424-9300       For Information call: DUDLEY 732-886-3100       
      DUDLEY CORPORATION
           	   125 Kenyon Drive
       				         	   Lakewood, New Jersey 08701
Effective Date: January 1, 2025
1. PRODUCT ID: Syn:  Phenazone 	CAS No.: 60-80-0 	E-C No.:200-486-6	 Weight:  188.23g/mol Formula: C11H12N2O

2. HAZARDS ID: GHS:	Acute Toxicity, Oral (Category 4)	
 Pictogram: 				                    
Signal Word:         WARNING
HAZARD STATEMENT(S): H302: Harmful if swallowed.	

PRECAUTIONARY STATEMENT(S) : P264: Wash skin thoroughly after handling P270: Do not eat, drink or smoke when using this product.  P330: Rinse Mouth. P301 + P312: If Swallowed: Call a poison center or doctor/physician if you feel unwell. P501: Dispose of contents/container to an approved waste disposal plant.

HMIS Classification: Health hazard  2, Flammability   0,  Physical hazards   0			
NFPA Rating: Health hazard  2, Fire     0, Reactivity hazard   0
2.3: Other Hazards: none

3. COMPOSITION: 
Chemical 				 CAS No.	 	Percent		
2-Amino-5-Chlorobenzoic acid	                   635-21-2                 98%                  

4. FIRST AID: Eyes: Flush eyes w/ water for 15 minutes, occasionally lifting the eyelids. Consult physician. 
Skin: flush skin with soap & water. Consult physician. Ingestion: Rinse mouth with water. Never give anything to an unconscious person. Consult Physician. Inhalation: Remove to fresh air immediately. If not breathing, give artificial respiration. Consult physician. Physician: Treat symptomatically & supportively.

5. FIRE FIGHTING: Info: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH, & full PPE. Irritating & highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing: use water spray to cool fire expose containers.  Use water spray, alcohol-resistant foam, dry chem or carbon dioxide. Hazard: Carbon & Nitrogen oxides Flash Pt: Not applicable. Auto-ignition Temp: N/A. Explosion Limits: N/A

6. ACCIDENTAL RELEASE: Info: Use proper PPE as indicated in Section 8. Spills/Leaks:  Clean up spills immediately, observing precautions in the Protective Equipment section.  Avoid generating dusty conditions.  Provide ventilation. Sweep up, then place into a suitable disposal container.

7. HANDLING & STORAGE: Handling: Wash thoroughly after handling.  Use with adequate ventilation.  Avoid contact with eyes, skin, and clothing.  Keep container tightly closed.  Avoid ingestion and inhalation.
Storage: Keep container tightly closed when not in use.  Store in a cool, dry area away from incompatibles.

8. EXPOSURE: Facilities storing or utilizing this material should be equipped with an eyewash facility and safety shower. Use adequate ventilation to keep airborne concentrations low.
Chemical 			ACGIH		NIOSH		OSHA Final & Vacated PEL’s
Antipyrine			None listed	None listed	None listed	

PPE: Eyes:  Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN 166. Skin:  Wear appropriate protective gloves to prevent skin exposure. 0.11mm thick Clothing:  Wear appropriate protective clothing (lab coat, cover alls), to prevent skin exposure. Respirators:  Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149.  Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

9. PHYSICAL & CHEM: Appearance:  White to primrose yellow powder Melting Pt:  109–114°C (228-232˚F)  Boiling Pt:  319˚C (606˚F)  Relative Density:  1.19g/cm3 at 20˚C (68˚F)  Partition co-efficient: n-octanol/water: log Pow: 0.538

10. STABILITY & REACTIVITY: Stability: Stable under normal temp & storage conditions. Avoid:  Incompatibles, strong oxidants. Incompatibilities:  Strong oxidants.  Haz Decomp: see section 5

11. TOXICOLOGICAL INFO: RTECS: CD2450000 LD50/LC50:      Oral, rat:  LD50= 1750 mg/kg.
Carcinogenicity: CAS# 60-80-0: Not listed by ACGIH, IARC, NIOSH, NTP or OSHA. 
Mutagenicity:  DNA Inhibition:  Human HeLa cells 	Other Studies: Stomach irregularities

12. ECOLOGICAL:  LC50-Danio rerio (Zebra fish) >500mg/l 96h

13. DISPOSAL CONSIDERATIONS: Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. 

14. TRANSPORT INFO: Not regulated.

15. REGULATORY: SARA 311/312: Acute Health hazard / Chronic Health hazard
CERCLA Haz. Substances & corresponding RQ/TPQs None of the chemicals in material have an RQ/TPQ. 
Section 313 No chemicals are reportable under Section 313. 
STATE CAS#60-80-0  is not present on state lists from CA, PA, MA, MN, FL, or NJ. 
Pa Right to Know:	Phenazone  CAS#60-80-0 	NJ Right to Know:	Phenazone  CAS#60-80-0
California Prop 65:  No Significant Risk Level: None of the chemicals in this product are listed. 

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives 
Hazardous Symbols:  XN     WGK (Water Danger/Protection)CAS#60-80-0:  1 
Canada - DSL/NDSL CAS#60-80-0   is  listed on Canada’s DSL List.    Canada – WHMIS:  Not available.
CAS# 60-80-0    is not listed on Canada’s Ingredient Disclosure List. 

16. DISCLAIMER: DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information.