1-ADAMANTANAMINE HCL

Safety Data Sheet
Emergency Telephone Number: CHEMTREC 1-800-424-9300       For Information call: DUDLEY 732-886-3100       
      DUDLEY CORPORATION
           	125 Kenyon Drive
       				         	 Lakewood, New Jersey 08701
Effective Date: January 1, 2025
1. PRODUCT: Syn:  1-Adamantylamine HCl, 1-Aminoadamantane HCl CAS No.: 665-66-7 E-C No.:211-560-2	Weight:  187-71g/mol 	Formula: C10H17N.HCl

2. HAZARDS: GHS:	Acute toxicity, Oral (Category 4)	
 Pictogram: 				
Signal Word:         WARNING
HAZARD STATEMENT(S): H302: Harmful if swallowed	
PRECAUTIONARY STATEMENT(S): P264: wash skin thoroughly after handling P270: Do not drink, eat, smoke, when using this product. P330: Rinse mouth P301 + P312: If Swallowed: Call Poison Center or doctor/physician if you feel unwell
P501: Dispose of contents/container to an approved waste disposal plant.

HMIS: Health hazard  1, Flammability   0,  Physical hazards   0			
NFPA Rating: Health hazard  1, Fire     0, Reactivity hazard   0

Potential Effects: Eye: Risk of serious damage to eyes.	Skin: Harmful in contact with skin. Ingestion: Harmful if swallowed. 		Inhalation: Harmful by inhalation. 
2.3: Other Hazards: none

3. COMPOSITION: 
Chemical Name				 CAS No.	 	Percent		
1-Adamantanamine hydrochloride    		665-66-7                   99%                  

4. FIRST AID: Eyes: Flush eyes with plenty of water for precaution. Skin: Flush skin with plenty of soap and water. Consult physician Ingestion: If victim is conscious and alert, Rinse mouth with water. Consult physician. 
Inhalation: Remove from exposure to fresh air. If not breathing, give artificial respiration. Consult physician.
Physician: Treat symptomatically and supportively. 

5. FIRE FIGHTING: Info: wear a self-contained breathing apparatus in pressure-demand. MSHA/NIOSH & full PPE. Extinguishing: Use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam. Flash Pt: N/A   Auto-ignition Temp: N/A. Explosion Limits: N/A. Hazard: Carbon & nitrogen oxides, Hydrogen chloride gas.

6. ACCIDENTAL RELEASE: Info: Use proper PPE as indicated in Section 8. 
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. 

7. HANDLING & STORAGE: Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with skin and eyes. Do not ingest or inhale. 
Storage: Store in a cool, dry place. Store in a tightly closed container. 

8. EXPOSURE: Use adequate ventilation to keep airborne concentrations low. Facilities storing/utilizing this material be equipped with any eyewash facility & safety shower.

Chemical		ACGIH                 NIOSH                OSHA - FINAL & Vacated PELs 
1-Adamantanamine HCl	None listed            None listed           None listed 

PPE; Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN 166. Skin: Wear appropriate protective gloves to prevent skin exposure. 0.11mm nitrile Clothing: Wear appropriate protective clothing to prevent skin exposure. 
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. 

9. PHYSICAL & CHEM: Appearance: White powder  Melting Pt:  300˚C. 		 

10. STABILITY & REACTIVITY: Stability: Stable room temp.  closed container under normal storage and handling conditions.  Incompatibilities: Strong oxidizing agents.  Haz Decomp: See Section 5 under Fire

11. TOXICOLOGICAL: RTECS#: AU4375000	LD50/LC50: Oral, rat: LD50 = 800 mg/kg; 
Carcinogenicity: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. 

12 ECOLOGICAL: No information available. 

13. DISPOSAL CONSIDERATIONS: Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series:  None listed.	RCRA U-Series:  None listed.

14. TRANSPORT INFO: DOT:	Not regulated.   	IMDG: Not regulated	IATA: Not regulated

15. REGULATORY INFO: SARA 311/312:  Acute Health Hazard
Section 302 (RQ) & 302 (TPQ) None of the chemicals in this material/product have an RQ or TPQ. 
Section 313 No chemicals are reportable under Section 313. 
STATE CAS# 665-66-7 is not present on state lists from CA, MN, Ma, FL. 
PA Right to Know:	Amantadine HCl  CAS#665-66-7  Rev. Date:7/17/2007
NJ Right to Know:	Amantadine HCl  CAS#665-66-7 Rev. Date:7/17/2007
California WARNING: This product contains a chemical known to the State of CA to cause birth defects or other reproductive harm. Amantadine hydrochloride. 

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling In Accordance with EC Directives 
Hazard Symbols: XN WGK (Water Danger/Protection) CAS# 665-66-7: 2. 
Canada - DSL/NDSL CAS# 665-66-7 is listed on Canada’s NDSL List. 
Canada - WHMIS  WHMIS: Not available.  Canadian Ingredients Disclosure List 

16. DISCLAIMER INFO: DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information.