ACRIFLAVINE NEUTRAL
Safety Data Sheet
Emergency Telephone Number: CHEMTREC 1-800-424-9300	For Information call: DUDLEY 732-886-3100       
DUDLEY CORPORATION        
          	    125 Kenyon Drive	
        Lakewood, New Jersey 08701
Effective Date: January 1, 2025
1. PRODUCT ID: CAS No.:  8048-52-0               Weight:  259.73g/mol	Formula:  C14H14CIN3
Synonyms:  Euflavine;  3,6-Diamino-10-methylacridinium chloride mixt. w/ 3,6-diaminoacridine(proflavine)

2.HAZARDS ID:
GHS CLASSIFICATION 
Acute toxicity, Oral
Skin Irritation
Eye Irritation
Acute & Chronic Aquatic Hazard
Specific target organ toxicity – single exposure - respiratory	Category 4
Category 2
Category 2A
Category 2
Category 3	
 Pictogram 		                       
				                       	                 
Signal Word: 		 Warning
HAZARD STATEMENT(S): H302: Harmful if swallowed   H315: Causes skin irritation. H319: Causes serious eye irritation H335: May cause respiratory irritation. H411: Toxic to aquatic life with long lasting effects. 	
PRECAUTIONARY STATEMENT(S): P261: Avoid breathing dust/fume/gas/mist/vapors/spray. P264: Wash skin thoroughly after handling. P270: Do not drink, eat, smoke, when using this product. P271: Use only outdoors or in a well-ventilated area. P273: Avoid release into the environment. P280: Wear protective gloves / eye /face protection. P330: Rinse mouth. P301 + P312: If swallowed: Call Poison Center or doctor/physician if you feel unwell. P302 + P312: If on Skin: Wash with plenty of soap & water. P501: Dispose of contents/container to an approved waste disposal plant. P304 +P340: If inhaled remove person to fresh air and keep comfortable. P305 + P351 +P338: If in eyes: rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P332 +P337 +P313: If skin or eye irritation persists: get medical advice. P362: Take off contaminated clothing and wash before reuse. P391: collect spillage P403 +P233 – Store in well-ventilated place keep container tightly closed. P405: store locked up. 

HMIS CLASSIFICATION:  	Health hazard:    2, Flammability:       0, Physical hazards:  0			
NFPA RATING: Health hazard: 2, Fire:  0, Reactivity hazard:  0

Potential Effects:	Eyes: May cause eye irritation and possible burns. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.   Inhalation: May cause respiratory tract irritation. The toxicological properties of this material have not been fully investigated.
2.3: Other Hazards: none

3. COMPOSITION, INFO:
Chemical Name 			CAS No.			Percent		
 Acriflavine Neutral			8048-52-0		> 92%		     

4. FIRST AID: Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical attention immediately. Skin: In case of contact, flush skin with plenty of water for at least 15 minutes while removing contaminated clothes and shoes. Get medical attention if irritation develops or persists. Ingestion: If victim is conscious and alert, give 2-4 cupfulls of water or milk to drink. Do NOT induce vomiting. NEVER give anything by mouth to an unconscious person. Get medical attention if irritation or symptoms appear. Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Physician: Treat symptomatically and supportively.

5. FIRE FIGHTING: Info: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved or equivalent, and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.  Runoff from fire control or dilution water may cause pollution. Media: Use water spray to cool fire expose containers.  Use water spray, dry chemical, Carbon dioxide, or alcohol-resistant foam. Haz combustion: Carbon oxides, nitrogen oxides (NOx)

6. ACCIDENTAL RELEASE: Info: Use proper PPE as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the PPE section. Avoid generating dusty conditions. Provide ventilation. 

7. HANDLING & STORAGE: Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation.  Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container in a cool, dry, well-ventilated area away from incompatibles.   

8. EXPOSURE: Facilities storing or utilizing this material should be equipped with an eyewash facility and safety shower. Use adequate ventilation to keep airborne concentrations low.
Chemical 		 ACGIH	        	 NIOSH	                	IARC		OSHA - Final PEL’s
Acriflavine Neutral		 None listed	None listed	None listed	None listed

PPE: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator, when necessary. 

9. PHYSICAL & CHEM: Appearance: Orange to red to red-brown to dark-red powder Melting Pt:206 – 208° C  (403-406˚F)  Decomp Temp: No data  Solubility: Soluble in water. 

10. STABILITY & REACTIVITY: Stability: Stable at room temp. in closed containers under normal storage & handling conditions. Avoid: Dust generation, excess heat, incompatible material, strong oxidants. Incompatibilities: oxidizing agents. Haz Decomp: see section 5

11. TOXICOLOGICAL INFO: RTECS: AR9660000   LD50/LC50: N/A.
Carcinogencity: CAS#8048-52-0: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. 

12. ECOLOGICAL INFO: Toxicity: Toxic to aquatic life. LC50-Fathead minnow – 25mg/l-96h     EC50-Water flea – 22.1mg/l-48h

13. DISPOSAL CONSIDERATIONS: Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. 
RCRA P-Series: None listed. 	RCRA U-Series: None listed.
 
14. TRANSPORT INFO: Not regulated.

15. REGULATORY INFO: SARA 311/312: Acute health hazard  /Chronic health hazard
SARA Section 302 None of the chemicals in this product have a TPQ/RQ.
Section 313 No chemicals are reportable under Section 313. 
STATE CAS#8048-52-0   is not present on state lists from CA, PA, MA, MN, FL, or NJ. 
PA Right to Know: Acriflavine neutral   CAS# 8048-52-0 	NJ Right to Know:	Acriflavine neutral CAS# 8048-52-0
California No Significant Risk Level: None of the chemicals in this product are listed. 

EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives 
Hazardous Symbols:       XI    WGK (Water Danger/Protection) CAS# 8048-52-0:  No information available. 
Canada - DSL/NDSL CAS#8048-52-0 is not listed on Canada’s DSL List. 
Canada – WHMIS:  This product has a WHMIS classification D2B
CAS#8048-52-0 is not listed on Canada’s Ingredient Disclosure List. 

16. DISCLAIMER INFO: DUDLEY CORPORATION provides the information herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this.  Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION makes no representations or warranties, either expressed or implied, including without limitation and warranties of merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or reliance upon this information.